Juvia Pharma Drug reference

A labelled letter to prepare questions for the next appointment. It is not a personal dose. Read the disclaimer

Provigil 100 mg is a labeled tablet, timed to the shift

3 min readReviewed 31 October 2026. Updated
White modafinil tablet on a wake-promotion summary card in clinical light

Key facts

Strength on this pageModafinil 100 mg tablets
BrandProvigil
ScheduleIV (US)
Labeled usual200 mg morning (narcolepsy / OSA)
Shift work200 mg ~1 hour before the shift
Half-lifeAbout 15 hours after multiple doses
Peak2-4 hours; food can delay Tmax ~1 hour
Hepatic cutHalf dose if severe impairment

Checked against the current FDA label, named clinical trials, and the sources listed on this site.

01Narcolepsy starts at 200 mg each morning

Provigil for narcolepsy starts at 200 mg taken once a day in the morning. The dose may be 400 mg based on individual efficacy and tolerability. A 100 mg tablet may be used when a lower dose is needed. In most patients the dosing frequency is once per day. Provigil may be taken with or without food.

Generic modafinil 100 mg, thirty tablets, October 2026. GoodRx commonly lists the 100 mg x 90 quantity, priced at $1,658.37 average retail and $37.07 with a coupon; a thirty-count is not a third of that figure and has to be quoted on its own. Modafinil is a Schedule IV controlled substance in the United States, so refill timing is regulated. This site does not dispense, and does not print a Modalert price, because none is published.

Sources and how this letter was sealed

  1. FDA / DailyMed prescribing information, Provigil (modafinil) tablets, C-IV.
  2. Labeled doses: 200 mg morning (narcolepsy, OSA); 200 mg ~1 hour before shift (SWD); half dose in severe hepatic impairment.
  3. PK: Tmax 2-4 h; food delay ~1 h; effective t1/2 ~15 h after multiple doses.
  4. DailyMed Provigil entries.

Method in brief: open primary sources, annotate against the current FDA label, countersign by Dr. Nora Lindqvist, MD, then seal with a dated review. Full walk-through on the method page and editorial standards.

How to cite this page - Vancouver style

Juvia Pharma Drug Reference. Provigil 100 mg is a labeled tablet, timed to the shift [Internet]. Stockholm: Juvia Pharma; 21 October 2026 [cited 2026 Aug 21]. Available from: https://juviapharma.com/letters/modafinil/

Desk thread

Answers follow the U.S. Provigil prescribing information.

Nils-Olof W., Karlstad writes

Why talk about 100 mg when the leaflet says 200 mg in the morning?

Desk reply

Provigil for narcolepsy starts at 200 mg taken once a day in the morning. The dose may be 400 mg based on individual efficacy and tolerability. A 100 mg tablet may be used when a lower dose is needed. In most patients the dosing frequency is once per day. Provigil may be taken with or without food.

Birgitta H., Umea writes

Can I split a 200 mg tablet to match a 100 mg chart?

Desk reply

Provigil for narcolepsy starts at 200 mg taken once a day in the morning. The dose may be 400 mg based on individual efficacy and tolerability. A 100 mg tablet may be used when a lower dose is needed. In most patients the dosing frequency is once per day. Provigil may be taken with or without food.

Helmi T., Jyvaskyla writes

Is once a day enough, or should I take a second dose at noon?

Desk reply

Provigil for narcolepsy starts at 200 mg taken once a day in the morning. The dose may be 400 mg based on individual efficacy and tolerability. A 100 mg tablet may be used when a lower dose is needed. In most patients the dosing frequency is once per day. Provigil may be taken with or without food.

Pal E., Kristiansand writes

When can a narcolepsy chart move above 200 mg?

Desk reply

Provigil for narcolepsy starts at 200 mg taken once a day in the morning. The dose may be 400 mg based on individual efficacy and tolerability. A 100 mg tablet may be used when a lower dose is needed. In most patients the dosing frequency is once per day. Provigil may be taken with or without food.

Before you start, stop, or change any medicine mentioned above, run it past your prescriber or pharmacist - they hold your chart, this despatch does not. Desk notice.

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