Checked against the current FDA label, named clinical trials, and the sources listed on this site.
01Adult depression opens at 20 mg each morning
Adult Prozac for major depressive disorder starts at 20 mg taken in the morning. After several weeks the dose may be increased based on individual efficacy and tolerability. Doses above 20 mg may be given once daily in the morning or twice daily, morning and noon. The maximum recommended dose is 80 mg per day.
GoodRx average retail$9.00
GoodRx coupon print$9.00
Generic fluoxetine 20 mg x 30 capsules, GoodRx capsule table, 08 July 2026.
Generic fluoxetine 20 mg capsules, thirty count, October 2026. GoodRx listed 20 mg x 30 capsules at $9.00 retail and $9.00 with a coupon on 08 July 2026 - the coupon saves nothing here because the cash price is already low. The 20 mg tablet is a separate listing ($111.10 / $16.71), so check which form your prescription names. This site does not dispense.
Sources and how this letter was sealed
FDA prescribing information, Prozac (fluoxetine capsules).
Lilly Prozac U.S. PI: adult MDD 20 mg morning start; max 80 mg/day; MAOI 5-week / 14-day clocks.
Method in brief: open primary sources, annotate against the current FDA label,
countersign by Dr. Nora Lindqvist, MD, then seal with a dated review.
Full walk-through on the method page and
editorial standards.
How to cite this page - Vancouver style
Juvia Pharma Drug Reference. Prozac 20 mg capsules start most adult depression charts [Internet]. Stockholm: Juvia Pharma; 21 October 2026 [cited 2026 Aug 21]. Available from: https://juviapharma.com/letters/fluoxetine/
Desk thread
Answers follow the U.S. Prozac prescribing information.
Signe A., Vasteras writes
Should the first 20 mg capsule be taken in the morning?
Desk reply
Adult Prozac for major depressive disorder starts at 20 mg taken in the morning. After several weeks the dose may be increased based on individual efficacy and tolerability. Doses above 20 mg may be given once daily in the morning or twice daily, morning and noon. The maximum recommended dose is 80 mg per day.
Evelina D., Jonkoping writes
I missed two mornings. Do I take three capsules today?
Desk reply
Adult Prozac for major depressive disorder starts at 20 mg taken in the morning. After several weeks the dose may be increased based on individual efficacy and tolerability. Doses above 20 mg may be given once daily in the morning or twice daily, morning and noon. The maximum recommended dose is 80 mg per day.
Solveig N., Trondheim writes
When might my prescriber raise the dose above 20 mg?
Desk reply
Adult Prozac for major depressive disorder starts at 20 mg taken in the morning. After several weeks the dose may be increased based on individual efficacy and tolerability. Doses above 20 mg may be given once daily in the morning or twice daily, morning and noon. The maximum recommended dose is 80 mg per day.
Arvo K., Tartu writes
What is the highest daily fluoxetine dose on the label?
Desk reply
Adult Prozac for major depressive disorder starts at 20 mg taken in the morning. After several weeks the dose may be increased based on individual efficacy and tolerability. Doses above 20 mg may be given once daily in the morning or twice daily, morning and noon. The maximum recommended dose is 80 mg per day.
Before you start, stop, or change any medicine mentioned above, run it past your prescriber or pharmacist - they hold your chart, this despatch does not. Desk notice.
