Juvia Pharma Drug reference

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Five milligrams on the Levitra label

4 min readReviewed 31 October 2026. Updated
Orange vardenafil tablet with a thin blue QT checklist outline

Key facts

Labelled strength5 mg tablet
Brand / genericLevitra / vardenafil HCl
Usual label start10 mg about 60 minutes before activity
Half-lifeAbout 4-5 hours (parent and M1)
Tmax30 minutes to 2 hours, median 60
High-fat mealCmax down 18-50%
QT study59 men; 10 mg and 80 mg vs moxifloxacin
Ritonavir cap2.5 mg once in 72 hours

Checked against the current FDA label, named clinical trials, and the sources listed on this site.

0110 mg about 60 minutes before activity

As-needed Levitra for ED starts at 10 mg taken about 60 minutes before sexual activity. The as-needed dose may be 20 mg based on individual efficacy and tolerability. A 5 mg as-needed tablet may be used when a lower dose is needed. In most patients the maximum dosing frequency is once per day.

02An erection lasting more than 4 hours

An erection lasting more than 4 hours requires emergency care, whether or not it is painful. Priapism lasting longer than 6 hours can result in penile tissue damage and permanent loss of potency. Use Levitra with caution in men with conditions that may predispose them to priapism: sickle cell anemia, multiple myeloma, leukemia, or penile deformity such as angulation, cavernosal fibrosis, or Peyronie disease.

Generic vardenafil 5 mg, eight tablets, October 2026. The GoodRx Levitra table listed 5 mg x 30 at $1,093.22 average retail and $125.33 with a coupon on 06 July 2026. Staxyn 10 mg orally disintegrating tablets are a different product and price separately. This site does not dispense.

03When a nitrate was given after Levitra

Sublingual nitroglycerin 0.4 mg taken 1 hour after vardenafil 20 mg showed potentiated blood-pressure drops. The same potentiation was seen when the nitrate was taken 4 hours after vardenafil 20 mg. Heart-rate increases were seen at 1, 4, and 8 hours. Those effects were not seen when vardenafil 20 mg was taken 24 hours before the nitrate.

Sources and how this letter was sealed

  1. FDA, vardenafil hydrochloride tablets US prescribing information (Levitra and generics), sections 2, 4, 5, 6, 7, 12, 14.
  2. DailyMed vardenafil hydrochloride film-coated tablet
  3. Thorough QT crossover, 59 healthy men, vardenafil 10 mg and 80 mg vs moxifloxacin 400 mg (label section 12.2).
  4. North American and European fixed-dose ED trials, n=762 and n=803, 5/10/20 mg (label section 14.1).

Method in brief: open primary sources, annotate against the current FDA label, countersign by Dr. Nora Lindqvist, MD, then seal with a dated review. Full walk-through on the method page and editorial standards.

How to cite this page - Vancouver style

Juvia Pharma Drug Reference. Five milligrams on the Levitra label [Internet]. Stockholm: Juvia Pharma; 21 October 2026 [cited 2026 Aug 21]. Available from: https://juviapharma.com/letters/vardenafil/

Desk thread

Answers follow the U.S. Levitra prescribing information.

Bo Wikstrom, Skelleftea writes

If most adults start at 10 mg, when is 5 mg the first tablet?

Desk reply

As-needed Levitra for ED starts at 10 mg taken about 60 minutes before sexual activity. The as-needed dose may be 20 mg based on individual efficacy and tolerability. A 5 mg as-needed tablet may be used when a lower dose is needed. In most patients the maximum dosing frequency is once per day.

Jussi Rantanen, Kotka writes

How soon before activity do I take 5 mg?

Desk reply

As-needed Levitra for ED starts at 10 mg taken about 60 minutes before sexual activity. The as-needed dose may be 20 mg based on individual efficacy and tolerability. A 5 mg as-needed tablet may be used when a lower dose is needed. In most patients the maximum dosing frequency is once per day.

Hanne Frost, Herning writes

I keep nitroglycerin. How long after Levitra is a nitrate allowed?

Desk reply

Sublingual nitroglycerin 0.4 mg taken 1 hour after vardenafil 20 mg showed potentiated blood-pressure drops. The same potentiation was seen when the nitrate was taken 4 hours after vardenafil 20 mg. Heart-rate increases were seen at 1, 4, and 8 hours. Those effects were not seen when vardenafil 20 mg was taken 24 hours before the nitrate.

Before you start, stop, or change any medicine mentioned above, run it past your prescriber or pharmacist - they hold your chart, this despatch does not. Desk notice.

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