Juvia Pharma Drug reference

A short educational article, not advice tailored to your own medicines. Read the disclaimer

Creatinine clearance writes the gabapentin ceiling

3 min readReviewed 31 October 2026. Updated
Kidney CrCl step card next to gabapentin capsules

Key facts

Tablet on this note800 mg
PHN start300 mg
Usual PHN target1800 mg/day
Renal cutCrCl <60 mL/min
t½, normal kidneysAbout 5–7 h

Checked against the current FDA label, named clinical trials, and the sources listed on this site.

01Postherpetic neuralgia starts at 300 mg on day 1

Neurontin for postherpetic neuralgia starts at 300 mg on day 1. Day 2 is 300 mg twice a day. Day 3 is 300 mg three times a day. The dose may be increased up to 1800 mg per day given in three divided doses. An 800 mg tablet is a labelled strength.

Sources and how this letter was sealed

  1. FDA, Neurontin US PI: PHN titration; renal dosing table; t½ 5–7 h vs ~52 h at CrCl <30.

Method in brief: open primary sources, annotate against the current FDA label, countersign by Dr. Nora Lindqvist, MD, then seal with a dated review. Full walk-through on the method page and editorial standards.

How to cite this page - Vancouver style

Juvia Pharma Drug Reference. Creatinine clearance writes the gabapentin ceiling [Internet]. Stockholm: Juvia Pharma; 21 October 2026 [cited 2026 Aug 21]. Available from: https://juviapharma.com/postscripts/neurontin-renal-steps/

Desk thread

Answers follow the U.S. Neurontin prescribing information.

Heikki Laine, Joensuu writes

Why start at 300 mg if the tablet in the house is 800 mg?

Desk reply

Neurontin for postherpetic neuralgia starts at 300 mg on day 1. Day 2 is 300 mg twice a day. Day 3 is 300 mg three times a day. The dose may be increased up to 1800 mg per day given in three divided doses. An 800 mg tablet is a labelled strength.

Oskar Lindqvist, Ornskoldsvik writes

What is the maximum daily dose on the label?

Desk reply

Neurontin for postherpetic neuralgia starts at 300 mg on day 1. Day 2 is 300 mg twice a day. Day 3 is 300 mg three times a day. The dose may be increased up to 1800 mg per day given in three divided doses. An 800 mg tablet is a labelled strength.

Berit Moen, Hamar writes

How many times a day on day 3?

Desk reply

Neurontin for postherpetic neuralgia starts at 300 mg on day 1. Day 2 is 300 mg twice a day. Day 3 is 300 mg three times a day. The dose may be increased up to 1800 mg per day given in three divided doses. An 800 mg tablet is a labelled strength.

Before you start, stop, or change any medicine mentioned above, run it past your prescriber or pharmacist - they hold your chart, this despatch does not. Desk notice.