Juvia Pharma Drug reference

A short educational article, not advice tailored to your own medicines. Read the disclaimer

QT limits and why milk supply stays off-label

3 min readReviewed 31 October 2026. Updated
QT and lactation icons beside Motilium tablets

Key facts

Tablet10 mg
Daily ceiling30 mg
QT study+3.4 msec at 80 mg/day
Milk licenceNone
US statusNot FDA-approved
Medically reviewed by Dr. Nora Lindqvist, MD, Clinical pharmacology Peer reviewed

Checked against the current FDA label, named clinical trials, and the sources listed on this site.

01Milk excretion after Motilium 10 mg

Domperidone is excreted in human breast milk after oral Motilium 10 mg. Breast-fed infants receive less than 0.1% of the maternal weight-adjusted dose. Cardiac effects in the infant cannot be excluded. The decision is whether to discontinue breast-feeding or to discontinue Motilium. A 10 mg tablet is one labelled strength on that carton.

Sources and how this letter was sealed

  1. EMA / Motilium SmPC: QT, 30 mg/day, age >60, CYP3A4; milk <0.1% maternal dose.
  2. FDA: domperidone not approved for human use; lactation warnings.

Method in brief: open primary sources, annotate against the current FDA label, countersign by Dr. Nora Lindqvist, MD, then seal with a dated review. Full walk-through on the method page and editorial standards.

How to cite this page - Vancouver style

Juvia Pharma Drug Reference. QT limits and why milk supply stays off-label [Internet]. Stockholm: Juvia Pharma; 21 October 2026 [cited 2026 Aug 21]. Available from: https://juviapharma.com/postscripts/motilium-qt-milk/

Desk thread

Answers follow the EMA / MHRA Motilium 10 mg SmPC.

Monika Z., Klaipeda writes

Lactation consultant suggested 10 mg TID. Safe milk plan?

Desk reply

Domperidone is excreted in human breast milk after oral Motilium 10 mg. Breast-fed infants receive less than 0.1% of the maternal weight-adjusted dose. Cardiac effects in the infant cannot be excluded. The decision is whether to discontinue breast-feeding or to discontinue Motilium. A 10 mg tablet is one labelled strength on that carton.

Before you start, stop, or change any medicine mentioned above, run it past your prescriber or pharmacist - they hold your chart, this despatch does not. Desk notice.